Denovo membranous glomerulopathy in renal allograft.

Renal transplant is now the accepted mode of treatment of end stage renal disease (ESRD). The major causes of ESRD being diabetes mellitus, hypertension, glomerulonephritis, polycystic kidney disease and other/unknown. The most common glomerular disease in renal allograft biopsies is transplant glomerulopathy, i.e., those lesions related to transplant rejections. Other glomerulonephropathies (GN) also occur which are recurrences of GN the original disease which caused ESRD, diseases related to the donor and those without any explanation called denovo GN. One hundred five well documented cases of denovo occurrence of membranous GN in renal allograft have been reported in medical literature. We present a case from Pakistan where approximately 1,000 transplanted patients are being followed-up.